hrp0084p3-1141 | Puberty | ESPE2015

Does Treatment with GnRH Analogues Affect BMI in Children with Precocious or Early Puberty?

Madhusudhana Madhavi , Willingham Linda , Gupta Sanjay , Matthew Verghese

Background: Treatment of precocious puberty with GnRH analogues is well established. But there are concerns about weight gain in patients on this treatment. There have been conflicting reports about the effect of GnRH analogues on weight.Objective and hypotheses: To assess the change in BMI in children treated with GnRH analogues within a UK Endocrine Service and to analyse the patient/parent experience of the treatment.Method: A r...

hrp0084p3-1224 | Thyroid | ESPE2015

Transient Polyarthritis with Carbimazole Treatment

Madhusudhana Madhavi , Barraclough Mary , Baguley Elaine , Gupta Sanjay

Background: Antithyroid drugs such as carbimazole form the mainstay of medical management of hyperthyroidism in children. Parents are always warned about agranulocytosis, which is a rare side effect of these drugs. Development of arthralgia after starting antithyroid medication can be a disabling side effect and needs to be distinguished from the more serious antineutrophil cytoplasmic antibody (ANCA) positive vasculitis.Objective and hypotheses: Here we...